Correlations between Age and Hypertension on Diabetic Foot Ulcer
DOI:
https://doi.org/10.26911/theijmed.2023.08.02.07Abstract
Background: Diabetic foot ulcer is a wound located on the foot of a diabetic patient, which is related to peripheral neuropathy or arterial disease. Hypertension can be related to diabetic foot ulcer by its mechanism that caused peripheral artery disease. Age also can be the one of risk factors for diabetic foot ulcers, because aging occurs a reduction of insulin secretion, even insulin resistance. Insulin resistance occurs in macroangiopathy. The purpose of this study is to determine the correlation between age and hypertension with diabetic foot ulcers.
Subjects and Method: This was a cross-sectional study conducted at Arafah Islamic Hospital Rembang, Central Java. The dependent variable is diabetic ulcers. The independent variables were age and hypertension. A sample of diabetic patients using medical records from January 2022-June 2022. Data were collected using purposive sampling and analyzed using the Chi-Square test, and regression logistic test.
Results: Significant correlation was found between age (OR= 3.80; 95% CI= 1.38 to 10.57; p<0.001) and hypertension (OR= 8.12; 95% CI= 2.70 to 24.40; p<0.001) with a diabetic foot ulcer.
Conclusion: There is a significant correlation between age and hypertension with diabetic foot ulcers.
Keywords: age, hypertension, diabetes, diabetic foot ulcers.
Correspondence: Nining Lestari. Bachelor of Medicine, Muhammadiyah University of Surakarta. Jl. A. Yani, Mendungan, Pabelan, Kartasura, Sukoharjo 57162, Central Jawa, Indonesia. Email: nl209@ums.ac.id. Mobile: +62852-2939-0353
Indonesian Journal of Medicine (2023), 08(02): 179-185
https://doi.org/10.26911/theijmed.2023.08.02.07
References
Ahmad AF (2022). Kejadian dan faktor risiko ulkus diabetikum pada pasien diabetes melitus (dm) tipe 2 di Rsu Pku Muhammadiyah Yogyakarta (Doctoral dissertation, Universitas Islam Indonesia).
Alexiadou K, Doupis J (2012). Management of diabetic foot ulcers. Diabetes Ther. 3(1): 115.
AlRubeaan K, Al Derwish M, Ouizi S, Youssef AM, Subhani SN, Ibrahim HM, Alamri BN (2015). Diabetic foot complications and their risk factors from a large retrospective cohort study. PloS one. 10(5). e0124446.
de Boer IH, Bangalore S, Benetos A, Davis AM, Michos ED, Muntner P, Rossing P., et al. (2017). Diabetes and hypertension: a position statement by the american diabetes association. Diabetes Care. 40(9): 12731284. Doi: 10.2337/dci170026. PMID: 28830958.
Dinas Kesehatan Provinsi Jawa Tengah (2019). Profil Kesehatan Provinsi Jateng Tahun 2019. (24): 273–5.
Dinas Kesehatan Provinsi Jawa Tengah (2021). Profil Kesehatan Provinsi Jateng Tahun 2021. Dinas Kesehat Provinsi Jawa Tengah. (24):273–5.
Badan Pusat Statistik Kabupaten Rembang (2015). produk domestik regional bruto Kabupaten Rembang Tahun 20102014. BPS: Kabupaten Rembang.
Ferawati, Ira (2014). Faktor-faktor yang mempengaruhi terjadinya ulkus diabetikum pada pasien diabetes mellitus tipe 2 di Rsud Prof. Dr.Margono Soekarjo Purwokerto. Umsoed: Purwokerto.Hadisaputro S, Setyawan H. (2007). Epidemiologi dan faktor-faktor risiko terjadinya Diabetes Mellitus tipe 2. Dalam: Darmono, et all. editors. Naskah Lengkap Diabetes mellitus Ditinjau dari Berbagai Aspek Penyakit dalam dalam rangka Purna Tugas Prof Dr.dr.RJ Djokomoeljanto. Badan Penerbit Universitas Diponegoro Semarang, 2007. 133154.
Hameed M, Hafsa F, Khan MIH, Hamdani F, Malik U, Mehmood N (2018). Early age of onset of type 2 Diabetes and common risk factors among newly diagnosed people with type 2 Diabetes visiting diabetes clinic in Lahore General Hospital, Pakistan. In Diabetic Medicin.e 35: 200200. 111 River St, Hoboken 070305774, NJ USA: WILEY.
Huang ZH, Li SQ, Kou Y, Huang L, Yu T, Hu A (2019). Risk factors for the recurrence of diabetic foot ulcers among Diabetic patients: a meta‐analysis. Int. Wound J. 16(6): 13731382.
International Diabetes Federation (2021). IDF Diabetes Atlas 10th ed.
Jeyaraman K, Berhane T, Hamilton M, Chandra AP, Falhammar H (2019). Mortality in patients with diabetic foot ulcer: a retrospective study of 513 cases from a single Centre in the Northern Territory of Australia. BMC Endocr Disord. 19:1. Doi: 10.1186/s1290201803272.
Kementerian kesehatan RI (2015). INFODATIN Pusat Data dan Informasi Kementerian Kesehatan RI Situasi Kesehatan Remaja. 2015.
Khan MIH, Azhar U, Zubair F, Khan ZA (2018). Can we link foot ulcer with risk factors in diabetics A study in a tertiary care hospital. Pak J Med Sci. 34(6): 1375.
Leone S, Pascale R, Vitale M, Esposito S (2012). Epidemiology of diabetic foot. Infez Med. 20: 813
Münter C, Price P (2012). Diabetic foot ulcers, prevention, and treatment. Mount Waverley, Coloplast.
Nuswantari (1998). Kamus Kedokteran Dorland, (edisi 25). EGC.
Ole Brunner, Suddarth (2013). Buku Ajar Keperawatan Medikal Bedah Edisi 8(2). Jakarta EGC.Panganugraha IH (2015). Hubungan hipertensi dengan kejadian ulkus Diabetikum (Diabetic Foot Ulcer) pada pasien Diabetes Melitus Tipe 2 di RSUD dr. Soedomo Kab. Trenggalek (Doctoral dissertation, University of Muhammadiyah Malang).
Pastore D, DejaSimoni A, De Stefano A, Pacifici F, Cela E, Infante M, Coppola A., et al. (2022). Risk factors for diabetic foot ulcers: an Albanian retrospective study of inpatients with type 2 diabetes.
Papatheodorou K, Banach M, Bekiari E, Rizzo M, Edmonds M (2018). Complications of diabetes 2017. J. Diabetes Res. Waspadji S (2014). Komplikasi kronik diabetes: Mekanisme terjadinya, diagnosis, dan strategi pengelolaan. Dalam Setiati S, Alwi I, Sudoyo AW, Simadibrata M, Setiyohadi B, Syam AF. Buku ajar ilmu penyakit dalam. Edisi ke 6. Jakarta: Pusat Penerbitan Ilmu Penyakit Dalam FKUI. pp 235966.
Windarto (2007). Kencing Manis (Diabetik). Jakarta: PT Sunda Kelapa Pustaka.
Yazdanpanah L, Shahbazian H, Nazari I, Arti HR, Ahmadi F, Mohammadianinejad SE, Cheraghian B, et al. (2018). Incidence and risk factors of diabetic foot ulcer: A population-based diabetic foot cohort (ADFC Study) two-year follow-up study. Int J Endocrinol. 15: 7631659. Doi: 10.1155/2018/7631659.