Atypical Spinal Tuberculosis of Upper Thoracic Spine: A Rare Case Report
Abstract
Background: Tuberculous infection is one of the most common pulmonary infection in developing countries, including Indonesia. Spinal tuberculosis is one of the most common extra¬pulmonary tuberculosis manifestation, accounting for 5% of all extrapulmonary spread, and 50% of all osteoarticular involvement. The aim of this study is to evaluate and how diagnosis and treatment to prevent over or under-diagnosis and explain about excellent management without any late complication further.
Case Presentation: A 20-year-old male with a history of weakness of both of his leg for 20 days prior to admission. From these examinations, patient was then diagnosed with pathological fracture 2nd thoracic vertebral body suspected due to atypical spinal tuberculosis. Patient was then undergone surgical debridement, decompression, stabilization and fusion.
Results: Patient was then undergone surgical debridement, decompression stabilization fusion. During the exposure at level C6 through Th4, no abscess was found. Transpedicular debridement at level Th2 was then done after the insertion of pedicle screws at level C6-Th1 and Th3-Th4, and again no abscess was present, however, a granulomatous mass was present on the location of 2nd thoracic vertebral body, located on the anterior right side of the spinal cord outside the dura mater.
Conclusion: Atypical presentation of spinal tuberculosis with the sole clinical manifestation of neurological deficit below affected level. The definitive treatment such as surgical debridement, stabilization and fusion must be consider.
Keywords: spinal, infection, tuberculosis, young patient.
Correspondence: I Gusti Lanang Ngurah Agung Artha Wiguna. Division of Spine, Department of Orthopaedic & Traumatology, Prof. I.G.N.G Ngoerah Hospital, Faculty of Medicine, Udayana University, Bali, Indonesia. Email:lanangwiguna20021979@gmail.com. Mobile: 0811388859.
Indonesian Journal of Medicine (2022), 07(03): 289-297
https://doi.org/10.26911/theijmed.2022.07.03.05
References
Babhulkar SS, Tayade W, Babhulkar SK (1984). Atypical spinal tuberculosis. J Bone Joint Surg Br. 66(2): 239–242. Doi: 10.1302/0301620X.66B2.6707060.
Cardoso MJ, Helgeson MD, Paik H, Dmitriev AE, Jr RAL, Rosner MK (2010). Structures at risk from pedicle screws in the proximal thoracic spine: computed tomography evaluation. Spine J. 10(10): 905–909. Doi: 10.1016/j.spinee.2010.08.020.
Cormican L (2006). Current difficulties in the diagnosis and management of spinal tuberculosis. Postgrad Med J. 82(963): 46–51. Doi: 10.1136/pgmj.2005.032862.
Garg RK, Somvanshi DS (2011). Spinal tuberculosis: A review. J Spinal Cord Med. 34(5): 440–454. Doi: 10.1179/2045772311Y.0000000023.
Gautam MP, Karki P, Rijal S, Singh R (2005). Pott’s spine and paraplegia. J Nepal Med Assoc. 44(159): 106115. PMID: 16570378. Paramarta IGE, Purniti PS, Subanada IB, Astawa P (2008). Spondilitis Tuberkulosis. Sari Pediatri. 10(3): 177183. Doi: 10.14238/sp10.3.2008.17783.Houston A, Macallan DC (2014). Extrapulmonary tuberculosis. Medicine 42(1): 18–22. Doi: 10.1016/j.mpmed.2013.10.008.
Kawsar HI, Gopalakrishna KV (2013). Spinal Tuberculosis uncommon but not unseen. Infectdis. 21(3): 192–195. Doi: 10.1097/IPC.0b013e3182699210.
Khanna K, Sabharwal S (2019). Spinal tuberculosis: a comprehensive review for the modern spine surgeon. Spine J. 19(11): 1858–1870. Doi: 10.1016/j.spinee.2019.05.002.
Kim JH, Ahn JY, Jeong SJ, Ku NS, Choi JY, Kim YK, Yeom JS et al. (2019). Prognostic factors for unfavourable outcomes of patients with spinal tuberculosis in a country with an intermediate tuberculosis burden. Bone Joint J. 101(12): 1542–1549. Doi: 10.1302/0301620X.101B12.BJJ20190558.R1.
Meena S, Barwar N, Gupta T, Chowdhury B (2014). Spinal Tuberculosis Presenting as Abdominal Pain: Rare Presentation of a Common Disease. Oman Med J 29(2). Doi: 10.5001/omj.2014.40.
Merino P, Candel FJ, Gestoso I, Baos E, Picazo J (2012). Microbiological diagnosis of spinal tuberculosis. Int Orthop. 36(2): 233–238. Doi: 10.1007/s002640111461x.
Pande KC, Babhulkar SS (2002). Atypical Spinal Tuberculosis. Clin Orthop Relat Res. 398: 67–74. Doi: 10.1097/0000308620020500000010.
Patel R, Gannamani V, Shay E, Alcid D (2016). Spinal Tuberculosis and Cold Abscess without Known Primary Disease: Case Report and Review of the Literature. Case Rep Infect Dis. 1–4. Doi: 10.1155/2016/1780153.
Portillo GL, Morris SL, Panduro A (2000). Rapid and efficient detection of extrapulmonary Mycobacterium tuberculosis by PCR analysis. Int J tuberc lung dis. 4(4): 361–70. PMID: 10777087. Rajasekaran S, Soundararajan DCR, Shetty AP, kanna RM (2018). Spinal Tuberculosis: Current Concepts. Global Spine J. 8: 96S108S. Doi: 10.1177/2192568218769053.
Ren H, Jiang J, Wang J, Qu DB, Chen JT (2016). Is duration of preoperative antituberculosis treatment a risk factor for postoperative relapse or nonhealing of spinal tuberculosis? Eur Spine J. 25(12): 3875–3883. Doi: 10.1007/s0058601644962.
Rodriguez TSY, Renjifo ME, Medina FJ (2019). Extrapulmonary Tuberculosis: Pathophysiology and Imaging Findings. RadioGraphics. 39(7): 2023–2037. Doi: 10.1148/rg.2019190109.
Turgut M (2001). Spinal tuberculosis (Pott’s disease): its clinical presentation, surgical management, and outcome. A survey study on 694 patients. Neurosurg. Rev. 24(1): 813. Doi: 10.1007/PL00011973.
Wang Y, Hao D, Qian L, He X, Meng Y, Wang B (2020). Esophageal perforation following pedicle screw placement for the treatment of upper thoracic spinal tuberculosis: a case report and review of the literature. BMC Musculoskelet. Disord. 21(1): 756. Doi: 10.1186/s12891020037834.
Watt JP, Davis JH (2013). Percutaneous core needle biopsies: The yield in spinal tuberculosis. S Afr Med J. 104(1): 29. Doi: 10.7196/samj.6868.
Yang L, Liu Z (2013). Analysis and therapeutic schedule of the postoperative recurrence of bone tuberculosis. J Orthop Surg Res. 8(1): 47. Doi: 10.1186/1749799X847.