The Effect of Chayote Extract (Sechium edule) On Blood Pressure in Pregnant Women with Hypertension
Abstract
Background: Increased blood pressure of pregnant women during pregnancy is one of the high risks during pregnancy which can lead to preeclampsia, eclampsia to maternal and infant mortality. One of the treatments recommended by pregnant women is to consume foods containing potassium and flavonoids, namely squash. This study aimed to determine the effect of squash pumpkin on changes in blood pressure of hypertensive mothers in pregnancy in the health center in Semarang City area.
Subjects and Methods: This was an experimental study. The study was conducted at community health centers in Semarang, Central Java, from March to May 2018. A sample of 20 pregnant women who experienced hypertension in pregnancy was divided into two groups, control and treatment groups. The dependent variable was blood pressure. The independent variable was the extract of chayote. The data were analyzed by multiple linear regression.
Results: There were differences in systolic blood pressure before and after the administration of squash extract (p<0.001). There are differences in Diastolic blood pressure before and after the administration of squash extract (p <0.001).
Conclusion: Consuming chayote can make an effort to help lower blood pressure in pregnant women with hypertension.
Keywords: flavonoids, hypertension in pregnancy, potassium, squash, blood pressure.
Correspondence: Nur Alfi Fauziah. Postgraduate Midwifery Program, School of Health Polytechnics. Jl. Tirto Agung, Pedalangan, Banyumanik, Semarang City, 50268, Central Java, Indonesia. Email: nuralfifauziah24@yahoo.com.
Indonesian Journal of Medicine (2019), 4(3): 266-277
https://doi.org/10.26911/theijmed.2019.04.03.10
References
Rukiyah AI LY (2012). Asuhan Kebidanan Patologi Kebidanan, Jakarta: Trans Info Media.
Cudihy D, Lee RV (2009). The pathophysiology of pre-eclampsia: Current clinical concepts. 2: 576–582.
Dalimartha S, Purnama BT, Sutarina N, Mahendra B, Darmawan R (2008). Care Your Self Hipertensi, Jakarta: Penebar Plus.
Djaelani EKP (2015). Pengaruh Sari Buah Labu Siam Terhadap Perubahan Tekanan Darah Pada Lansia Penderita Hipertensi.
Etri Yanti RIS (2017). Pengaruh Pemberian Perasan Labu Siam (Secium Edule) terhadap Tekanan Darah pada Penderita Hipertensi. Jurnal Kesehatan Medika Saintika, 8(1).
Hernawati (2011). Sistem Renin Angiotens in Aldosteron: Perannya Dalam Pengaturan Tekanan Darah dan Hipertensi,
Nisa I (2012). Ajaibnya terapi herbal tumpas penyakit darah tinggi, Jakarta: Dunia Sehat.
Jayani I (2016). Pemberian Labu Siam Berimplikasi Terhadap Perubahan Tekanan Darah Ibu Hamil Preeklampsi., 4(2).
Erdman JW Jr, Balentine D, Arab L, Beecher G, Dwyer JT, Folts J, Harnly J, Hollman P, et al. (2018). Flavonoids and Heart Health: Proceedings of the ILSI North America Flavonoids Workshop, J Nutr. 137(1): 718S-737S. doi: 10.1093/jn/137.3.718S.
Health Service Offices of Semarang City, (2016). Profil Kesehatan Kota Semarang.
Health Service Offices of Central Java Province (2015). Profil Kesehatan Provinsi Jawa Tengah.
Kowalak (2011). Buku Ajar Patofisiologi, Jakarta: EGC.
LombardoEarl G, Roman-Ramos R, Zamilpa A, HerreraRuiz M, RosasSalgado G, Tortoriello J, and Jiménez-Ferrer E(2014). Extracts and Fractions from Edible Roots of Sechium edule (Jacq) Sw with Antihypertensive Activity. EvidenceBased Complementary and Alternative Medicine. 1-9. doi: 10.1155/2014/594359
Luh N, Fitriani C, Walanda DK (2012). Determination of Potassium (K) and Calcium (Ca) Content in Chayote (Sechium edule) and The Effects With its Growth Soil. 1: 174–180.
Hakim L (2015). Optimasi Dosis Aplikasi Farmakokinetik dalam Penemuan Obat dan Pengobatan, Bursa Ilmu.
Nadila F (2014). Antihypertensive Potential Of Chayote Fruit Extract Kandungan Labu Siam Potensi Flavonoid, 3: 34–38.
Nisa I (2013). Khasiat Sakti Tanaman Obat Untuk Darah Tinggi Cetakan 1, Jakarta: Dunia Sehat.
Nzelu D, Dumitrascu B, Hunt KF,Cordina M, Kametas NA (2017). Pregnancy outcomes in women with previous gestational hypertension: A cohort study to guide counselling and management. Pregnancy Hypertension. doi: 10.1016/j.preghy.2017.10.011.
Ogle R, Korda A (2015). Hypertension in pregnancy and long term cardiovascular mortality: a retrospective cohort study. American Journal of Obstetrics and Gynecology, (2016). doi: 10.1016/j.ajog.2015.12.047.
Pisani I, Tiralongo GM, Lo Presti D, Gagliardi G, Farsetti D, Vasapollo B3, Novelli GP, Andreoli A, Valensise H, (2017). Correlation between Maternal Body Composition and Haemodynamic Changes in Pregnancy: Different Profiles for Different Hypertensive
Disorders. Pregnancy Hypertension: An International Journal of Women’s Cardiovascular Health. doi: 10.1016/j.preghy.2017.07.149.
Paramawati RHDRD (2016). Khasiat Ajaib Daun Advokat, Jakarta: Penebar swadaya.
Roberts LM,Davis GK, Homer CS (2017). Pregnancy with gestational hypertension or preeclampsia: A qualitative exploration of women’s experiences. Midwifery, 46: 17–23. doi: 10.1016/j.midw.2017.01.004.
Pereira ARA, Velho APM, Cortez DAG, Szerwieski LLD, Cortez LER (2016). Traditional use of medicinal plants by elderly. Revista da Rede de Enfermagem do Nordeste, 17(3).
Malik VKR (2016). Hypertension in Pregnancy. Springer International Publishing Switzerland.
Nugroho T (2012). Patologi Kebidanan Cetakan 2, Yogyakarta: Nuha Medika.
Tjoawirawan NB (2012). The Effect of Chayote (Sechium edule Swartz) On Blood Pressure.
Vest AR, Cho LS (2014). Hypertension in Pregnancy. Springer Science. doi: 10.10 07/s11883-013-0395-8.
Kwon EK, Lee DY, Lee H, Kim DO, Baek NI, Kim YE, Kim HY (2010). Flavonoids From The Buds Of Rosa Damascena Inhibit The Activity Of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase and Angiotensin I-Converting Enzyme. 882–886.
World Health Organization (2013). A Global Brief on Hypertension.
Yuninda E (2009). The Effect of Labu Siam Juice (Sechium edule) on Female Blood Pressure.
