Effect of Purple Sweet Potato (Ipomoea Batatas L.) on Reducing Renal Tissue Damage of House Mice (Mus Musculus L.) After Excessive Physical Exercise

Authors

  • Rika Nailuvar Sinaga Faculty of Sport Science, Medan University, Indonesia
  • Herla Rusmarilin Faculty of Agriculture, University of North Sumatera, Indonesia
  • T.Helvi Mardiani Faculty of Medicine, University of North Sumatera, Indonesia
  • Ayu Elvana Health Polytechnic Medan, Indonesia

Abstract

Background: Heavy physical exercise can reduce blood flow and metabolism in kidney that eventually release free radicals. The free radicals can form oxydative stress and damage renal tissue. Exogenous antioxydant administration is usually recommended to minimize the renal tissue damage. This study aimed to examined the effect of purple sweet potato (Ipomoiea batatas L.) extract on renal tissue damage

References

Birben E, Sahiner UM, Sackesen C, Erzurum S, Kalayci O (2012). Oxidative Stress and Antioxidant Defense. WAO Journal: 9-19.

Bucioli SA, Abreu LC, Valenti VE, Leone C, Vannucchi H (2011). Effects of vitamin E supplementation on renal nonenzymatic antioxidants in young rats submitted to exhaustive exercise stress. BMC Complementary and Alternative Medicine, 11:133.

Daniel RM, Dragomir C, Stelian S (2010). The effect of acute physical exercise on liver and kidney in the Wistar rat. Romanian Biotechnological Letters, 15(3):51-55.

Kocer G, Senturk UK, Kuru O, Gunduz F (2008). Potential sources of oxidative stress that induce postexercise proteinuria in rats. J Appl Physiol, 104: 1063-1068.

Kumar, Abbas, Fausto, Mitchell (2007). Robbins Basic Pathology (8th ed.). Philadelphia : Elsevier.

Manurung RD (2011). Tesis : Manfaat Pemberian Madu terhadap Perubahan Ureum dan Kreatinin serta Makroskopik Ginjal dan Histopatologi Tubulus Proksimal Ginjal Mencit (Mus musculus L) Jantan yang diberi Rhodamin B. Universitas Sumatera Utara. Medan.

Nangaku M (2006). Chronic Hypoxia and Tubulointerstitial Injury: A Final Common Pathway to End-Stage Renal Failure. American Society of Nephro-logy,17:17-25.

Okolow MP, Dziegiel P, Gomulkiewicz A, Kisiela D, Krajewska BD, Jethon Z, Carraro U (2006). Exerciseinduced apoptosis in rat kidney is mediated by both angiotensin II AT1 and AT2 receptors. Histology and Histopathology, 21:459-466.

Pojer E, Mattivi F, Johnson, Stockley CS (2013). The Case for Anthocyanin Consumption to Promote Human Health: A Review. Institute of food technologists, 12:483-508.

Prior RL (2003). Fruits and vegetables in the prevention of cellular oxidative damage. Am J Clin Nutr, 78:570S-8S.

Radak Z, Zhao Z, Koltai E, Ohno H, Atalay M (2013). Oxygen Consumption and Usage During Physical Exercise: The Balance Between Oxidative Stress and ROS-Dependent Adaptive Signaling. Antioxidants & Redox Signaling, 18(10): 1208-1246.

Richana N (2013). Menggali potensi ubi kayu dan ubi jalar. Edisi kedua. Bandung: Nuansa Cendikia.

Sreedevi A, Pavani B (2012). Effect of anthocyanin fraction on cisplatininduced nephrotoxicity. IJRAP, 3(4):587-590.

Urso ML, Clarkson PM (2003). Oxidative stress, exercise, and antioxidant supplementation.Toxicology;189(12):41-54.

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